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Call us: 1.866.416.0516

Email us: [email protected]

Extrel

MAX300-BIO Bioreactor Gas Analyzer

Fast, Accurate, Efficient

Mass Spectrometry is a powerful tool for bioreactor monitoring. Changes to the composition of bioreactor or fermentor off-gas provide crucial insight into cellular health and production efficiency. This makes the fast, accurate analysis of CO2, O2, N2, Ar, H2O and other compounds essential for real-time process control.

The MAX300-BIO uses cutting edge quadrupole mass spectrometer technology to quantify bioreactor gases from multiple reactors within the facility and reports the data to the control system in real-time.

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Description

Description

Fast, Accurate, Efficient

Mass Spectrometry is a powerful tool for bioreactor monitoring. Changes to the composition of bioreactor or fermentor off-gas provide crucial insight into cellular health and production efficiency. This makes the fast, accurate analysis of CO2, O2, N2, Ar, H2O and other compounds essential for real-time process control.

The MAX300-BIO uses cutting edge quadrupole mass spectrometer technology to quantify bioreactor gases from multiple reactors within the facility and reports the data to the control system in real-time.

OVERVIEW

  • Measures CO2, O2, N2, H2O, alcohols, contaminants, and more
  • Samples without risk of contamination
  • Calculates control parameters in real-time (e.g. Respiratory Quotient)
  • Provides flow and mass balance data
  • Multiport sample systems for up to 80+ reactors
  • High precision and accuracy for optimal process automation
  • Low maintenance, utilities and calibration required
  • Complete method scale-up
  • Lab, Pilot, Production

SYSTEM SPECS

Mass Range Options

  • 1-250, 300, 500 amu

Detectable Compounds

  • Any gas or vapor sample

Detection Range

  • 100% – 10 ppm standard, 10 ppb with the electron multiplier option*

Number of Sample Streams

  • 16, 31, 40 or 80+

Analysis Rate

  • <0.4 seconds per component

Number of Components

  • Unlimited

Number of Analysis Routines

  • Unlimited

Number of User Configurable Data Tags

  • Unlimited

Analysis Precision

  • <0.25% Relative Standard Deviation**

Stability

  • <0.5% Relative Standard Deviation over 30 days**

Filaments

  • Two, one active and one spare with automatic switchover

Maintenance

  • Typically two PMs per year

Manual or fully automated calibration and validation

*Matrix dependent. Documented on trace benzene in air

**Based on the analysis of 1% argon

Product Notes

MAX300-BIO PRODUCT NOTE IPB100A 

Documentation

FERMENTATION FAST FACTS IFO101A 
ATEX CERTIFICATION 
IECEX CERTIFICATION 

Publications

A SIMPLE NOVEL APPROACH FOR REAL-TIME MONITORING OF SODIUM GLUCONATE PRODUCTION BY ON-LINE PHYSIOLOGICAL PARAMETERS IN BATCH FERMENTATION BY ASPERGILLUS NIGER 
PRECISION BREEDING FOR RNAI SUPPRESSION OF A MAJOR 4-COUMARATE:COENZYME A LIGASE GENE IMPROVES CELL WALL SACCHARIFICATION FROM FIELD GROWN SUGARCANE 
OPTIMIZATION OF THE N-PROPANOL CONCENTRATION AND FEEDBACK CONTROL STRATEGY WITH ELECTRONIC NOSE IN ERYTHROMYCIN FERMENTATION PROCESSES 
COMBINED 13C-ASSISTED METABOLOMICS AND METABOLIC FLUX ANALYSIS REVEALS THE IMPACTS OF GLUTAMATE ON THE CENTRAL METABOLISM OF HIGH SS-GALACTOSIDASE-PRODUCING PICHIA PASTORI 
THE ONLINE MORPHOLOGY CONTROL AND DYNAMIC STUDIES ON IMPROVING VITAMIN B12 PRODUCTION BY PSEUDOMONAS DENITRIFICANS WITH ONLINE CAPACITANCE AND SPECIFIC OXYGEN CONSUMPTION RATE 
CONTROLLING THE FEED RATE OF PROPANOL TO OPTIMIZE ERYTHROMYCIN FERMENTATION BY ON-LINE CAPACITANCE AND OXYGEN UPTAKE RATE MEASUREMENT 
BLOCKING THE FLOW OF PROPIONATE INTO TCA CYCLE THROUGH A MUTB KNOCKOUT LEADS TO A SIGNIFICANT INCREASE OF ERYTHROMYCIN PRODUCTION BY AN INDUSTRIAL STRAIN OF SACCHAROPOLYSPORA ERYTHRAEA 

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